Programs
Thursday, November 6, 2008
7:00-9:00 Welcome Reception
Friday, November 7, 2008
8:00-8:15 Welcome
• Robert H. Dworkin, PhD (University of Rochester)
Moderator: Gary J. Bennett, PhD (McGill University)
8:15-9:00 Keynote address: Visceral pain and its mechanisms
• Gerald F. Gebhart, PhD (University of Pittsburgh)
NEUROPATHIC PAIN MECHANISMS
9:00-9:25 Epigenetic and experiential factors in the expression of pain
• Wendy F. Sternberg, PhD (Haverford College)
9:25-9:50 The role of descending inhibition and facilitation in neuropathic pain
• Frank Porreca, PhD (University of Arizona)
9:50-10:30 COFFEE BREAK
10:30-10:55 Complex Regional Pain Syndrome, type I: pain due to microvascular pathology?
• Gary J. Bennett, PhD (McGill University)
10:55-11:20 Animal models of neuropathic pain and its treatment: limitations and prospects for improvement
• Jeffrey S. Mogil, PhD (McGill University)
11:20-12:00 Audience discussion with panel
• G. Bennett, G. Gebhart, J. Mogil, F. Porreca, W. Sternberg
12:15-1:15 Supported Lunch Symposium: Neuropathic vs. Non-neuropathic Pain
- 12:15-12:35 Similarities and differences in mechanisms
• Clifford J. Woolf, MD, BCh, PhD (Harvard University) - 12:35-12:55 Simlarities and differences in treatment
• Mark S. Wallace, MD (University of California San Diego) - 12:55-1:15 Audience discussion with speakers
NEUROPATHIC PAIN SYNDROMES
Moderator: Ralf Baron, Dr. med. (University of Kiel)
1:30-1:55 Diabetic, IGT-associated, and idiopathic peripheral neuropathies: one, two, or three chronically painful conditions?
• Dan Ziegler, MD (Heinrich Heine University)
1:55-2:20 Inherited painful and non-painful neuropathies and their implications for understanding neuropathic pain
• John W. Griffin (Johns Hopkins University)
2:20-3:00 COFFEE BREAK
3:00-3:25 Central neuropathic pain: an update
• Gunnar L. Wasner, Dr. med. (University of Kiel)
3:25-3:50 Vulvodynia and other chronic pelvic pain conditions
• David C. Foster, MD (University of Rochester)
3:50-4:30 Audience discussion with panel
• D. Foster, J. Griffin, G. Wasner, D. Ziegler
4:30-6:00 POSTER SESSION
With cash bar and appetizers
DINNER WORKSHOP A: Meet the Experts–Treating Refractory Neuropathic Pain (additional cost)
Moderator: Michael C. Rowbotham, MD (University of California San Francisco)
7:00 Dinner
7:15-7:30 Refractory neuropathic pain: case presentation
• Michael C. Rowbotham, MD (University of California San Francisco)
7:30-7:40 Anesthesiology perspective
• Christopher D. Wells, MD, FRCA (University of Liverpool)
7:40-7:50 Neurology perspective
• Michael C. Rowbotham, MD (University of California San Francisco)
7:50-8:00 Psychiatry perspective
• Edward Covington, MD (Cleveland Clinic)
8:00-8:10 Neurosurgery perspective
• Robert M. Levy, MD, PhD (Northwestern University)
8:10-9:00 Audience discussion with the panel
• E. Covington, R. Levy, M. Rowbotham, C. Wells
DINNER WORKSHOP B: What is “Breakthrough” Neuropathic Pain and How Should it be Treated? (additional cost)
Moderator: Dennis C. Turk, PhD (University of Washington)
7:00 Dinner
7:15-7:35 What do we know about “breakthrough” neuropathic pain?
• David M. Simpson, MD (Mt. Sinai School of Medicine, New York)
7:35-7:55 Medical perspective: how should “breakthrough” neuropathic pain be treated?
• Brett R. Stacey, MD (Oregon Health & Science University)
7:55-8:15 Psychosocial perspective: how should “breakthrough” neuropathic pain be treated?
• Dennis C. Turk, PhD (University of Washington)
8:15-8:35 Breakthrough pain: a regulatory perspective
• Bob A. Rappaport, MD (United States Food and Driug Administrationr)
8:35-9:00 Audience discussion with the panel
• D. Simpson, B. Stacey, B. Rappaport, D. Turk
DINNER WORKSHOP C: The ABCs of Getting an NIH Grant to Study Pain (limited to 20 participants with preference given to new investigators; additional cost)
Moderator: Jennifer Haythornthwaite, PhD (Johns Hopkins University)
7:00 Dinner
7:15-8:00 What’s necessary to succeed at NIH grants: an NIH perspective
• Linda Porter, PhD (National Institute of Neurological Disorders and Stroke)
8:00-8:20 Successful NIH grants: what I’ve learned as an academic
• Jennifer Haythornthwaite, PhD (Johns Hopkins University)
8:20-8:40 Successful NIH grants: what I’ve learned serving on study sections
• Srinivasa N. Raja, MD (Johns Hopkins University)
8:40-9:00 Audience discussion with the panel
• J. Haythornthwaite, L. Porter, S. Raja
Saturday, November 8, 2008
Moderator: Srinivasa N. Raja, MD (Johns Hopkins University)
8:00-8:45 Keynote address: When is chronic low back pain neuropathic?
• Ralf Baron, Dr. med. (University of Kiel)
RECENT ADVANCES IN THE TREATMENT OF NEUROPATHIC PAIN
8:45-9:10 Mechanisms of existing and emerging treatments for neuropathic pain: is the pipeline drying up?
• Roy Freeman, MD (Harvard University)
9:10-9:35 Neural blockade and spinal cord stimulation: their place in the neuropathic pain treatment algorithm
• Srinivasa N. Raja, MD (Johns Hopkins University)
9:35-10:15 COFFEE BREAK
With continued poster session
10:15-10:40 Neurosurgical approaches to the treatment of patients with neuropathic pain
• Robert M. Levy, MD, PhD (Northwestern University)
10:40-11:05 The impact of neuropathic pain on health-related quality of life
• Jennifer Haythornthwaite, PhD (Johns Hopkins University)
11:05-11:45 Audience discussion with panel
• R. Baron, R. Freeman, J. Haythornthwaite, R. Levy, S. Raja
12:00-1:00 Supported Lunch Symposium: Fibromyalgia
- 12:00-12:20 Do the neurobiology and psychology of fibromyalgia provide support for considering it a neuropathic pain condition?
• Daniel J. Clauw, MD (University of Michigan)
- 12:20-12:40 Advances in the treatment of fibromyalgia
• Leslie J. Crofford, MD (University of Kentucky )
- 12:40-1:00 Audience discussion with speakers
ROUNDTABLE: From Mechanisms to Medicines: Clinical Trial Designs for Identifying Analgesics for Neuropathic Pain
Moderator: Karin L. Petersen, MD (University of California San Francisco)
1:15-1:40 Research design considerations for futility studies and other adaptive clinical trial methods
• Bernard Ravina, MD, MSCE (University of Rochester)
1:40-2:05 Single-dose and other proof-of-concept clinical trial designs in patients with neuropathic pain
• Karin L. Petersen (University of California San Francisco)
2:05-2:45 COFFEE BREAK
2:45-3:10 Can imaging identify analgesic medications for neuropathic pain?
• Irene Tracey, PhD (Oxford University)
3:10-3:35 Discussant: An industry perspective on early clinical evaluations of analgesic medications for neuropathic pain
• R. Michael Poole, MD (Wyeth)
3:35-4:15 Audience discussion with panel
• K. Petersen, M. Poole, B. Ravina, I. Tracey